Browsing by Author "Gaddy, Dana"
Now showing items 1-9 of 9
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Mitchell, Alexis (2017-07-28)The main goal of regenerative medicine is to enhance the innate healing response to more closely mimic tissue development. This may include cell-based, trophic, or small molecule therapies. In cell-based therapies, the ...
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Gaddy, Dana (Texas A&M University, 1985)Not available
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Bertels, Joshua Clarence (2023-08-03)Hypophosphatasia (HPP) is a rare inherited disorder that is due to inactivation of the tissue-nonspecific alkaline phosphatase (ALP) gene ALPL. There are more than 400 different mutations in the human ALPL gene that ...
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Loughran, Allister; Gaddy, Dana; Beenken, Karen; Meeker, Daniel; Morello, Roy; Zhao, Haibo; Byrum, Stephanie; Tackett, Alan; Cassat, James; Smeltzer, Mark (Infection and Immunity, 2016)
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Mata Lopez, Sara (2020-04-16)Duchenne (DMD) and golden retriever (GRMD) muscular dystrophy are genetically homologous conditions caused by mutations in the DMD gene, with loss of the protein dystrophin. There’s currently no cure for DMD, although some ...
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Bedi, Yudhishtar (2021-11-08)This dissertation examines the effect of paternal alcohol consumption on fetal growth and on the sperm epigenetic and noncoding RNA profile. Earlier studies have found links between paternal preconception alcohol consumption ...
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Dolan, Connor Patrick (2019-02-20)In the past two decades, several groups have shown that the mammalian digit tip regeneration is peripheral nerve-dependent. However, there is a serious gap in this body of literature as no one has characterized the ...
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Michaud, Danielle Renee (2022-06-02)Griscelli Syndrome type 1 (GS1) is an ultra-rare, autosomal recessive human disease that affects vesicle and membrane trafficking caused by a mutation in the Myosin-Va gene. Myosin-Va is an unconventional motor protein ...
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Ketcham, Paulina Dean (2018-01-18)Compared to amphibians like the Axolotl, mammals display limited endogenous regenerative ability. However, the digit tips of mice, humans, and other primates possess some regenerative capabilities, providing hope that ...